China (Mainland)
Fat Burning Femara Anti Estrogen Letrozole Breast Cancer CAS 112809-51-5 CAS NO.112809-51-5
- Min.Order: 10 Gram
- Payment Terms: L/C,T/T,MoneyGram,Other
- Product Details
Keywords
- 112809-51-5 Letrozole
- 112809-51-5 Letrozole 98%
- 112809-51-5 White crystalline powder
Quick Details
- ProName: Fat Burning Femara Anti Estrogen Letro...
- CasNo: 112809-51-5
- Molecular Formula: C17H11N5
- Appearance: White crystalline powder
- Application: Pharmaceutical intermediates
- DeliveryTime: Within 5-7 work days after confirming ...
- PackAge: according to customer's requirement
- Port: Shanghai
- ProductionCapacity: 500 Kilogram/Month
- Purity: 98%
- Storage: cool and dry
- Transportation: EMS, DHL, FedEx,TNT
- LimitNum: 10 Gram
Superiority
Run-Biotech provides a broad and integrated portfolio of services throughout the drug R&D process. Our services are designed to help our worldwide customers shorten the discovery and development time and lower the cost of drug and medical device R&D through cost-effective and efficient outsourcing solutions.
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Run-Biotech has further enhanced the integrated services with analytical services, bio-analytical services, process research, process development services, API manufacturing services, discovery biology, pharmacology, formulation services, biologics manufacturing services, antibody, biological research reagent manufacturing and sales services.
Run-Biotech has its own logistics center, provides the professional, personalized one-stop services, offers a variety of technologies and products and services for the world's major technology and industrial customers.
Run-Biotech has a professional team with rich creative talents, every day there will be new technologies and new products.Run-Biotech is committed to the production and sales of high-purity organic, analytical reagents, standard substances, organometallic catalysts, pharmaceutical intermediates, as well as ultra fine materials. We are able to provide small quantities, varieties of raw materials at very high speed , meeting the needs of experimental, pilot scale as well as large-scale production.
Details
Detail
Product name:Letrozole
Alias: Femara, Letrozole, TROZET
CAS Registry Number:112809-51-5
Purity: 98%
MF: C17H11N5
MW: 285.3
Character: White crystalline powder.
Delivery: EMS, DHL, TNT, FedEx, UPS
Other drugs in same class:Anastrozole,Letrozole,Tamoxifen citrate,Exemestane
Usage: Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from Letrozole include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system.
Description
| Product name | Letrozole |
| Other name | Femara, Letrozole, TROZET |
| CAS register number | 112809-51-5 |
| Molecular formula | C17H11N5 |
| Molecular weight | 285.3 |
| Molecular structure |
|
| Assay | 98% |
| Appearance | White crystalline powder |
| Package | 1kg/aluminium foil bag or as required |
| Usage | can be used as pharmaceutical material |
| Shipping | By express courier |
| Payment options | , MoneyGram, T/T |
| Price | Negotiated |
Application
Letrozole has been used for ovarian stimulation by fertility doctors since 2001 because it has fewer side-effects than clomiphene (Clomid) and less chance of multiple gestation. A Canadian study presented at the American Society of Reproductive Medicine 2005 Conference suggested that letrozole may increase the risk of birth defects.[citation needed] A more detailed ovulation induction follow-up study found that letrozole, compared with a control group of clomiphene, had significantly lower congenital malformations and chromosomal abnormalities at an overall rate of 2.4% (1.2% major malformations) compared with clomiphene 4.8% (3.0% major malformations). Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants.In 2012, an Indian parliamentary committee said that the drug controller office colluded with letrozole's makers to approve the drug for infertility in India and also stated that letrozole's use for infertility was illegal worldwide; however, such off-label uses are legal in many countries such as the US and UK.
The anti-estrogen action of letrozole has been shown to be useful in pretreatment for termination of pregnancy, in combination with misoprostol. It can be used in place of mifepristone, which is expensive and unavailable in many countries.
Letrozole is sometimes used as a treatment for gynecomastia, although it is probably most effective at this if caught in an early stage (such as in users of anabolic steroids).
Letrozole has also been shown to delay the fusing of the growth plates in mice.When used in combination with growth hormone, letrozole has been shown effective in one adolescent boy with a short stature.
Specification
| Tests | Specifications | Results |
| Appearance | White or off-white crystaline powder |
White |
|
Solubility |
Soluble in Chloroform; |
Conform |
| ldentification |
(1)Maximum absorption in wavelength of 240 nm |
Conform |
| (2)Infrared spectrum should be in accordance the dominant peak of contrast | In accordance with the dominant peak of contrast | |
| Melting points | 182℃-184℃ | 182℃ |
| Related substances | ≤0.5% | 0.3% |
| Single impurity | ≤0.3% | 0.2% |
| Loss on drying | ≤1.0% | 0.8% |
|
[Assay]C17H11N5 |
≥98.0% | 99.2% |
| Conclusion | Conforms Specifications of Enterprise Standard. | |